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N-Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases

[Image: see text] In light of the global antimicrobial-resistance crisis, there is an urgent need for novel bacterial targets and antibiotics with novel modes of action. It has been shown that Pseudomonas aeruginosa elastase (LasB) and Clostridium histolyticum (Hathewaya histolytica) collagenase (Co...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Konstantinović, Jelena, Yahiaoui, Samir, Alhayek, Alaa, Haupenthal, Jörg, Schönauer, Esther, Andreas, Anastasia, Kany, Andreas M., Müller, Rolf, Koehnke, Jesko, Berger, Fabian K., Bischoff, Markus, Hartmann, Rolf W., Brandstetter, Hans, Hirsch, Anna K. H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429951/
https://ncbi.nlm.nih.gov/pubmed/32470298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c00584
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