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Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T

Clostridial collagenases are among the most efficient enzymes to degrade by far the most predominant protein in the biosphere. Here we present crystal structures of the peptidases of three clostridial collagenase isoforms (ColG, ColH, and ColT). The comparison of unliganded and liganded structures r...

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Autors principals: Eckhard, Ulrich, Schönauer, Esther, Brandstetter, Hans
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711286/
https://ncbi.nlm.nih.gov/pubmed/23703618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.448548
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