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Chemically programmable and switchable CAR-T therapy
Although the cell surfaceome is predominantly targeted and drugged with antibodies, its pocketome fraction is only accessible to small molecules and constitutes a rich subset of binding sites with immense potential diagnostic and therapeutic utility. Compared to antibodies, however, small molecules...
Gardado en:
| Publicado en: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7429910/ https://ncbi.nlm.nih.gov/pubmed/32329959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202005432 |
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