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N-glycolyl chondroitin synthesis using metabolically engineered E. coli
N-glycolyl chondroitin (Gc-CN) is a metabolite of N-glycolylneuraminic acid (Neu5Gc), a sialic acid that is commonly found in mammals, but not humans. Humans can incorporate exogenous Neu5Gc into their tissues from eating red meat. Neu5Gc cannot be biosynthesized by humans due to an evolutionary mut...
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| Publicado en: | AMB Express |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7429809/ https://ncbi.nlm.nih.gov/pubmed/32803432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-020-01084-6 |
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