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N-glycolyl chondroitin synthesis using metabolically engineered E. coli

N-glycolyl chondroitin (Gc-CN) is a metabolite of N-glycolylneuraminic acid (Neu5Gc), a sialic acid that is commonly found in mammals, but not humans. Humans can incorporate exogenous Neu5Gc into their tissues from eating red meat. Neu5Gc cannot be biosynthesized by humans due to an evolutionary mut...

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Detalhes bibliográficos
Publicado no:AMB Express
Main Authors: Awofiranye, Adeola E., Baytas, Sultan N., Xia, Ke, Badri, Abinaya, He, Wenqin, Varki, Ajit, Koffas, Mattheos, Linhardt, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429809/
https://ncbi.nlm.nih.gov/pubmed/32803432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-020-01084-6
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