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The role of TDP-43 mislocalization in amyotrophic lateral sclerosis

Since its discovery as a primary component in cytoplasmic aggregates in post-mortem tissue of patients with Amyotrophic Lateral Sclerosis (ALS), TAR DNA Binding Protein 43 kDa (TDP-43) has remained a central focus to understand the disease. TDP-43 links both familial and sporadic forms of ALS as mut...

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Foilsithe in:Mol Neurodegener
Main Authors: Suk, Terry R., Rousseaux, Maxime W. C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429473/
https://ncbi.nlm.nih.gov/pubmed/32799899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00397-1
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