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Structural biology of HIV integrase strand transfer inhibitors
Integrase (IN) strand transfer inhibitors (INSTIs) are recent compounds in the antiretroviral arsenal used against HIV. INSTIs work by blocking retroviral integration, an essential step in the viral lifecycle that is catalyzed by the virally encoded IN protein within a nucleoprotein assembly called...
Shranjeno v:
| izdano v: | Trends Pharmacol Sci |
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| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7429322/ https://ncbi.nlm.nih.gov/pubmed/32624197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2020.06.003 |
| Oznake: |
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