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Structural biology of HIV integrase strand transfer inhibitors
Integrase (IN) strand transfer inhibitors (INSTIs) are recent compounds in the antiretroviral arsenal used against HIV. INSTIs work by blocking retroviral integration, an essential step in the viral lifecycle that is catalyzed by the virally encoded IN protein within a nucleoprotein assembly called...
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| Publié dans: | Trends Pharmacol Sci |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7429322/ https://ncbi.nlm.nih.gov/pubmed/32624197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2020.06.003 |
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