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Structural biology of HIV integrase strand transfer inhibitors
Integrase (IN) strand transfer inhibitors (INSTIs) are recent compounds in the antiretroviral arsenal used against HIV. INSTIs work by blocking retroviral integration, an essential step in the viral lifecycle that is catalyzed by the virally encoded IN protein within a nucleoprotein assembly called...
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| Publicado no: | Trends Pharmacol Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7429322/ https://ncbi.nlm.nih.gov/pubmed/32624197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2020.06.003 |
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