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Acetylation of cytidine residues boosts HIV-1 gene expression by increasing viral RNA stability

Epitranscriptomic RNA modifications, including methylation of adenine and cytidine residues, are now recognized as key regulators of both cellular and viral mRNA function. Moreover, acetylation of the N(4) position of cytidine (ac4C) was recently reported to increase the translation and stability of...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Tsai, Kevin, Jaguva Vasudevan, Ananda Ayyappan, Campos, Cecilia Martinez, Emery, Ann, Swanstrom, Ronald, Cullen, Bryan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429276/
https://ncbi.nlm.nih.gov/pubmed/32533923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.05.011
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