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Acetylation of cytidine residues boosts HIV-1 gene expression by increasing viral RNA stability

Epitranscriptomic RNA modifications, including methylation of adenine and cytidine residues, are now recognized as key regulators of both cellular and viral mRNA function. Moreover, acetylation of the N(4) position of cytidine (ac4C) was recently reported to increase the translation and stability of...

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Bibliografski detalji
Izdano u:Cell Host Microbe
Glavni autori: Tsai, Kevin, Jaguva Vasudevan, Ananda Ayyappan, Campos, Cecilia Martinez, Emery, Ann, Swanstrom, Ronald, Cullen, Bryan R.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429276/
https://ncbi.nlm.nih.gov/pubmed/32533923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.05.011
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