Epitranscriptomic addition of m(5)C to HIV-1 transcripts regulates viral gene expression

How the covalent modification of mRNA ribonucleotides, termed epitranscriptomic modifications, alters mRNA function remains unclear. One issue has been the difficulty of quantifying these modifications. Using purified HIV-1 genomic RNA, we show that this RNA bears more epitranscriptomic modification...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Host Microbe
Egile Nagusiak: Courtney, David G., Tsai, Kevin, Bogerd, Hal P., Kennedy, Edward M., Law, Brittany A., Emery, Ann, Swanstrom, Ronald, Holley, Christopher L., Cullen, Bryan R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714563/
https://ncbi.nlm.nih.gov/pubmed/31415754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.07.005
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