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Epitranscriptomic addition of m(5)C to HIV-1 transcripts regulates viral gene expression

How the covalent modification of mRNA ribonucleotides, termed epitranscriptomic modifications, alters mRNA function remains unclear. One issue has been the difficulty of quantifying these modifications. Using purified HIV-1 genomic RNA, we show that this RNA bears more epitranscriptomic modification...

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Bibliografski detalji
Izdano u:Cell Host Microbe
Glavni autori: Courtney, David G., Tsai, Kevin, Bogerd, Hal P., Kennedy, Edward M., Law, Brittany A., Emery, Ann, Swanstrom, Ronald, Holley, Christopher L., Cullen, Bryan R.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714563/
https://ncbi.nlm.nih.gov/pubmed/31415754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.07.005
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