Tetrodotoxin‐Sensitive Neuronal‐Type Na(+) Channels: A Novel and Druggable Target for Prevention of Atrial Fibrillation

BACKGROUND: Atrial fibrillation (AF) is a comorbidity associated with heart failure and catecholaminergic polymorphic ventricular tachycardia. Despite the Ca(2+)‐dependent nature of both of these pathologies, AF often responds to Na(+) channel blockers. We investigated how targeting interdependent N...

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Xehetasun bibliografikoak
Argitaratua izan da:J Am Heart Assoc
Egile Nagusiak: Munger, Mark A., Olğar, Yusuf, Koleske, Megan L., Struckman, Heather L., Mandrioli, Jessica, Lou, Qing, Bonila, Ingrid, Kim, Kibum, Ramos Mondragon, Roberto, Priori, Silvia G., Volpe, Pompeo, Valdivia, Héctor H., Biskupiak, Joseph, Carnes, Cynthia A., Veeraraghavan, Rengasayee, Györke, Sándor, Radwański, Przemysław B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429002/
https://ncbi.nlm.nih.gov/pubmed/32468902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.015119
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