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Resolving Peto’s paradox: Modeling the potential effects of size‐related metabolic changes, and of the evolution of immune policing and cancer suppression
The intrinsic risk of cancer increases with body size and longevity; however, big long‐lived species do not exhibit this increase, a contradiction named Peto's paradox. Five hypotheses potentially resolving this paradox were modeled using the multistage model of carcinogenesis. The five hypothe...
Zapisane w:
| Wydane w: | Evol Appl |
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| 1. autor: | |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
John Wiley and Sons Inc.
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7428811/ https://ncbi.nlm.nih.gov/pubmed/32821274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/eva.12993 |
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