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A metabolic perspective of Peto's paradox and cancer

The frequency of cancer is postulated to be proportional to the number of cells an animal possesses, as each cell is similarly exposed to mutagens with every cell division. Larger animals result from more cell divisions with more mutagenic exposure, and hence are expected to have higher frequencies...

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Détails bibliographiques
Publié dans:Philos Trans R Soc Lond B Biol Sci
Auteur principal: Dang, Chi V.
Format: Artigo
Langue:Inglês
Publié: The Royal Society 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581028/
https://ncbi.nlm.nih.gov/pubmed/26056367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0223
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