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A metabolic perspective of Peto's paradox and cancer

The frequency of cancer is postulated to be proportional to the number of cells an animal possesses, as each cell is similarly exposed to mutagens with every cell division. Larger animals result from more cell divisions with more mutagenic exposure, and hence are expected to have higher frequencies...

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Detalhes bibliográficos
Publicado no:Philos Trans R Soc Lond B Biol Sci
Autor principal: Dang, Chi V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581028/
https://ncbi.nlm.nih.gov/pubmed/26056367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0223
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