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A metabolic perspective of Peto's paradox and cancer

The frequency of cancer is postulated to be proportional to the number of cells an animal possesses, as each cell is similarly exposed to mutagens with every cell division. Larger animals result from more cell divisions with more mutagenic exposure, and hence are expected to have higher frequencies...

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Pubblicato in:Philos Trans R Soc Lond B Biol Sci
Autore principale: Dang, Chi V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581028/
https://ncbi.nlm.nih.gov/pubmed/26056367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2014.0223
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