Interleukin-26, preferentially produced by T(H)17 lymphocytes, regulates CNS barrier function

OBJECTIVE: To investigate the involvement of interleukin (IL)-26 in neuroinflammatory processes in multiple sclerosis (MS), in particular in blood-brain barrier (BBB) integrity. METHODS: Expression of IL-26 was measured in serum, CSF, in vitro differentiated T helper (T(H)) cell subsets, and postmor...

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Pubblicato in:Neurol Neuroimmunol Neuroinflamm
Autori principali: Broux, Bieke, Zandee, Stephanie, Gowing, Elizabeth, Charabati, Marc, Lécuyer, Marc-André, Tastet, Olivier, Hachehouche, Lamia, Bourbonnière, Lyne, Ouimet, Jean-Philippe, Lemaitre, Florent, Larouche, Sandra, Cayrol, Romain, Bouthillier, Alain, Moumdjian, Robert, Lahav, Boaz, Poirier, Josée, Duquette, Pierre, Arbour, Nathalie, Peelen, Evelyn, Prat, Alexandre
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428369/
https://ncbi.nlm.nih.gov/pubmed/32788322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000870
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