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The IL‐27/IL‐27R axis is altered in CD4(+) and CD8(+) T lymphocytes from multiple sclerosis patients

OBJECTIVES: Pro‐ and anti‐inflammatory properties have been attributed to interleukin‐27 (IL‐27). Nevertheless, the impact of this cytokine on chronic inflammatory diseases such as multiple sclerosis (MS) remains ill‐defined. We investigated the biology of IL‐27 and its specific receptor IL‐27Rα in...

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Bibliografiska uppgifter
I publikationen:Clin Transl Immunology
Huvudupphovsmän: Clénet, Marie‐Laure, Laurent, Cyril, Lemaitre, Florent, Farzam‐kia, Negar, Tastet, Olivier, Devergne, Odile, Lahav, Boaz, Girard, Marc, Duquette, Pierre, Prat, Alexandre, Larochelle, Catherine, Arbour, Nathalie
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934284/
https://ncbi.nlm.nih.gov/pubmed/33728050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1262
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