The IL‐27/IL‐27R axis is altered in CD4(+) and CD8(+) T lymphocytes from multiple sclerosis patients

OBJECTIVES: Pro‐ and anti‐inflammatory properties have been attributed to interleukin‐27 (IL‐27). Nevertheless, the impact of this cytokine on chronic inflammatory diseases such as multiple sclerosis (MS) remains ill‐defined. We investigated the biology of IL‐27 and its specific receptor IL‐27Rα in...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Clénet, Marie‐Laure, Laurent, Cyril, Lemaitre, Florent, Farzam‐kia, Negar, Tastet, Olivier, Devergne, Odile, Lahav, Boaz, Girard, Marc, Duquette, Pierre, Prat, Alexandre, Larochelle, Catherine, Arbour, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934284/
https://ncbi.nlm.nih.gov/pubmed/33728050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1262
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