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The IL‐27/IL‐27R axis is altered in CD4(+) and CD8(+) T lymphocytes from multiple sclerosis patients

OBJECTIVES: Pro‐ and anti‐inflammatory properties have been attributed to interleukin‐27 (IL‐27). Nevertheless, the impact of this cytokine on chronic inflammatory diseases such as multiple sclerosis (MS) remains ill‐defined. We investigated the biology of IL‐27 and its specific receptor IL‐27Rα in...

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Publicat a:Clin Transl Immunology
Autors principals: Clénet, Marie‐Laure, Laurent, Cyril, Lemaitre, Florent, Farzam‐kia, Negar, Tastet, Olivier, Devergne, Odile, Lahav, Boaz, Girard, Marc, Duquette, Pierre, Prat, Alexandre, Larochelle, Catherine, Arbour, Nathalie
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934284/
https://ncbi.nlm.nih.gov/pubmed/33728050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1262
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