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Signaling Events Involved in Interleukin 27 (IL-27)-induced Proliferation of Human Naive CD4(+) T Cells and B Cells
IL-27 induces stronger proliferation of naive than memory human B cells and CD4(+) T cells. In B cells, this differential response is associated with similar levels of IL-27 receptor chains, IL-27Rα and gp130, in both subsets and stronger STAT1 and STAT3 activation by IL-27 in naive B cells. Here, w...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149329/ https://ncbi.nlm.nih.gov/pubmed/21669870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.221010 |
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