Interleukin-15 enhances proinflammatory T-cell responses in patients with MS and EAE

OBJECTIVE: We posit that interleukin-15 (IL-15) is a relevant contributor to MS pathobiology as this cytokine is elevated in the CNS and periphery of patients with MS. We aim to investigate (1) the impact of IL-15 on T lymphocytes from patients with MS and (2) the in vivo role of IL-15 using the exp...

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Pubblicato in:Neurol Neuroimmunol Neuroinflamm
Autori principali: Laurent, Cyril, Deblois, Gabrielle, Clénet, Marie-Laure, Carmena Moratalla, Ana, Farzam-kia, Negar, Girard, Marc, Duquette, Pierre, Prat, Alexandre, Larochelle, Catherine, Arbour, Nathalie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7745728/
https://ncbi.nlm.nih.gov/pubmed/33323466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000931
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