Dual role of ALCAM in neuroinflammation and blood–brain barrier homeostasis

Activated leukocyte cell adhesion molecule (ALCAM) is a cell adhesion molecule found on blood–brain barrier endothelial cells (BBB-ECs) that was previously shown to be involved in leukocyte transmigration across the endothelium. In the present study, we found that ALCAM knockout (KO) mice developed...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Lécuyer, Marc-André, Saint-Laurent, Olivia, Bourbonnière, Lyne, Larouche, Sandra, Larochelle, Catherine, Michel, Laure, Charabati, Marc, Abadier, Michael, Zandee, Stephanie, Haghayegh Jahromi, Neda, Gowing, Elizabeth, Pittet, Camille, Lyck, Ruth, Engelhardt, Britta, Prat, Alexandre
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2017
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PNAS Plus
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278491/
https://ncbi.nlm.nih.gov/pubmed/28069965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614336114
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