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Human adiponectin receptor AdipoR1 assumes closed and open structures

The human adiponectin receptors, AdipoR1 and AdipoR2, are key anti-diabetic molecules. We previously reported the crystal structures of human AdipoR1 and AdipoR2, revealing that their seven transmembrane helices form an internal closed cavity (the closed form). In this study, we determined the cryst...

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Dades bibliogràfiques
Publicat a:Commun Biol
Autors principals: Tanabe, Hiroaki, Fujii, Yoshifumi, Okada-Iwabu, Miki, Iwabu, Masato, Kano, Kuniyuki, Kawana, Hiroki, Hato, Masakatsu, Nakamura, Yoshihiro, Terada, Takaho, Kimura-Someya, Tomomi, Shirouzu, Mikako, Kawano, Yoshiaki, Yamamoto, Masaki, Aoki, Junken, Yamauchi, Toshimasa, Kadowaki, Takashi, Yokoyama, Shigeyuki
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427782/
https://ncbi.nlm.nih.gov/pubmed/32796916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01160-4
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