Human adiponectin receptor AdipoR1 assumes closed and open structures

The human adiponectin receptors, AdipoR1 and AdipoR2, are key anti-diabetic molecules. We previously reported the crystal structures of human AdipoR1 and AdipoR2, revealing that their seven transmembrane helices form an internal closed cavity (the closed form). In this study, we determined the cryst...

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Vydáno v:Commun Biol
Hlavní autoři: Tanabe, Hiroaki, Fujii, Yoshifumi, Okada-Iwabu, Miki, Iwabu, Masato, Kano, Kuniyuki, Kawana, Hiroki, Hato, Masakatsu, Nakamura, Yoshihiro, Terada, Takaho, Kimura-Someya, Tomomi, Shirouzu, Mikako, Kawano, Yoshiaki, Yamamoto, Masaki, Aoki, Junken, Yamauchi, Toshimasa, Kadowaki, Takashi, Yokoyama, Shigeyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427782/
https://ncbi.nlm.nih.gov/pubmed/32796916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01160-4
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