AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice

Adiponectin receptors, AdipoR1 and AdipoR2 exert anti-diabetic effects. Although muscle-specific disruption of AdipoR1 has been shown to result in decreased insulin sensitivity and decreased exercise endurance, it remains to be determined whether upregulation of AdipoR1 could reverse them in obese d...

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Pubblicato in:Commun Biol
Autori principali: Iwabu, Masato, Okada-Iwabu, Miki, Tanabe, Hiroaki, Ohuchi, Nozomi, Miyata, Keiko, Kobori, Toshiko, Odawara, Sara, Kadowaki, Yuri, Yokoyama, Shigeyuki, Yamauchi, Toshimasa, Kadowaki, Takashi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794315/
https://ncbi.nlm.nih.gov/pubmed/33420419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01579-9
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