AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice

Adiponectin receptors, AdipoR1 and AdipoR2 exert anti-diabetic effects. Although muscle-specific disruption of AdipoR1 has been shown to result in decreased insulin sensitivity and decreased exercise endurance, it remains to be determined whether upregulation of AdipoR1 could reverse them in obese d...

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Publicat a:Commun Biol
Autors principals: Iwabu, Masato, Okada-Iwabu, Miki, Tanabe, Hiroaki, Ohuchi, Nozomi, Miyata, Keiko, Kobori, Toshiko, Odawara, Sara, Kadowaki, Yuri, Yokoyama, Shigeyuki, Yamauchi, Toshimasa, Kadowaki, Takashi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794315/
https://ncbi.nlm.nih.gov/pubmed/33420419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01579-9
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