Human adiponectin receptor AdipoR1 assumes closed and open structures

The human adiponectin receptors, AdipoR1 and AdipoR2, are key anti-diabetic molecules. We previously reported the crystal structures of human AdipoR1 and AdipoR2, revealing that their seven transmembrane helices form an internal closed cavity (the closed form). In this study, we determined the cryst...

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Detaylı Bibliyografya
Yayımlandı:Commun Biol
Asıl Yazarlar: Tanabe, Hiroaki, Fujii, Yoshifumi, Okada-Iwabu, Miki, Iwabu, Masato, Kano, Kuniyuki, Kawana, Hiroki, Hato, Masakatsu, Nakamura, Yoshihiro, Terada, Takaho, Kimura-Someya, Tomomi, Shirouzu, Mikako, Kawano, Yoshiaki, Yamamoto, Masaki, Aoki, Junken, Yamauchi, Toshimasa, Kadowaki, Takashi, Yokoyama, Shigeyuki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427782/
https://ncbi.nlm.nih.gov/pubmed/32796916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01160-4
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