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Short Hairpin RNAs for Strand-Specific Small Interfering RNA Production

RNA interference (RNAi) is an effective mechanism for inhibiting gene expression at the post-transcriptional level. Expression of a messenger RNA (mRNA) can be inhibited by a ∼22-nucleotide (nt) small interfering (si)RNA with the corresponding reverse complementary sequence. Typically, a duplex of s...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Sheng, Peike, Flood, Krystal A., Xie, Mingyi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427337/
https://ncbi.nlm.nih.gov/pubmed/32850763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00940
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