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The Axial Alignment of Titin on the Muscle Thick Filament Supports Its Role as a Molecular Ruler

The giant protein titin is expressed in vertebrate striated muscle where it spans half a sarcomere from the Z-disc to the M-band and is essential for muscle organisation, activity and health. The C-terminal portion of titin is closely associated with the thick, myosin-containing filament and exhibit...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Bennett, Pauline, Rees, Martin, Gautel, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427331/
https://ncbi.nlm.nih.gov/pubmed/32619437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.06.025
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