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Myosin binding protein-C activates thin filaments and inhibits thick filaments in heart muscle cells
Myosin binding protein-C (MyBP-C) is a key regulatory protein in heart muscle, and mutations in the MYBPC3 gene are frequently associated with cardiomyopathy. However, the mechanism of action of MyBP-C remains poorly understood, and both activating and inhibitory effects of MyBP-C on contractility h...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4284530/ https://ncbi.nlm.nih.gov/pubmed/25512492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413922112 |
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