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Stress-dependent activation of myosin in the heart requires thin filament activation and thick filament mechanosensing
Myosin-based regulation in the heart muscle modulates the number of myosin motors available for interaction with calcium-regulated thin filaments, but the signaling pathways mediating the stronger contraction triggered by stretch between heartbeats or by phosphorylation of the myosin regulatory ligh...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8072254/ https://ncbi.nlm.nih.gov/pubmed/33850019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023706118 |
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