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Myosin light chain phosphorylation enhances contraction of heart muscle via structural changes in both thick and thin filaments
Contraction of heart muscle is triggered by calcium binding to the actin-containing thin filaments but modulated by structural changes in the myosin-containing thick filaments. We used phosphorylation of the myosin regulatory light chain (cRLC) by the cardiac isoform of its specific kinase to elucid...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889392/ https://ncbi.nlm.nih.gov/pubmed/27162358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602776113 |
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