Colon Cancer-Associated Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon Tumors via the Circulatory System

Fusobacterium nucleatum is a common oral bacterium that is enriched in colorectal adenomas and adenocarcinomas (CRC). In humans, high fusobacterial CRC abundance is associated with chemoresistance and poor prognosis. In animal models, fusobacteria accelerate CRC progression. Targeting F. nucleatum m...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Abed, Jawad, Maalouf, Naseem, Manson, Abigail L., Earl, Ashlee M., Parhi, Lishay, Emgård, Johanna E. M., Klutstein, Michael, Tayeb, Shay, Almogy, Gideon, Atlan, Karine A., Chaushu, Stella, Israeli, Eran, Mandelboim, Ofer, Garrett, Wendy S., Bachrach, Gilad
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cellular and Infection Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7426652/
https://ncbi.nlm.nih.gov/pubmed/32850497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00400
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