Fap2 Mediates Fusobacterium nucleatum Colorectal Adenocarcinoma Enrichment by Binding to Tumor-Expressed Gal-GalNAc

Fusobacterium nucleatum is associated with colorectal cancer and promotes colonic tumor formation in preclinical models. However, fusobacteria are core members of the human oral microbiome and less prevalent in the healthy gut, raising questions about how fusobacteria localize to CRC. We identify a...

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Foilsithe in:Cell Host Microbe
Main Authors: Abed, Jawad, Emgård, Johanna E.M., Zamir, Gideon, Faroja, Mouhammad, Almogy, Gideon, Grenov, Amalie, Sol, Asaf, Naor, Ronit, Pikarsky, Eli, Atlan, Karine A., Mellul, Anna, Chaushu, Stella, Manson, Abigail L., Earl, Ashlee M., Ou, Nora, Brennan, Caitlin A., Garrett, Wendy S., Bachrach, Gilad
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465824/
https://ncbi.nlm.nih.gov/pubmed/27512904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.07.006
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