Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack

Bacteria, such as Fusobacterium nucleatum, are present in the tumor microenvironment. However, the immunological consequences of intra-tumoral bacteria remain unclear. Here, we have shown that natural killer (NK) cell killing of various tumors is inhibited in the presence of various F. nucleatum str...

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Publicado no:Immunity
Main Authors: Gur, Chamutal, Ibrahim, Yara, Isaacson, Batya, Yamin, Rachel, Abed, Jawad, Gamliel, Moriya, Enk, Jonatan, Bar-On, Yotam, Stanietsky-Kaynan, Noah, Coppenhagen-Glazer, Shunit, Shussman, Noam, Almogy, Gideon, Cuapio, Angelica, Hofer, Erhard, Mevorach, Dror, Tabib, Adi, Ortenberg, Rona, Markel, Gal, Miklić, Karmela, Jonjic, Stipan, Brennan, Caitlin A., Garrett, Wendy S., Bachrach, Gilad, Mandelboim, Ofer
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361732/
https://ncbi.nlm.nih.gov/pubmed/25680274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.01.010
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