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Mouse TIGIT inhibits NK-cell cytotoxicity upon interaction with PVR
The activity of natural killer (NK) cells is controlled by a balance of signals derived from inhibitory and activating receptors. TIGIT is a novel inhibitory receptor, recently shown in humans to interact with two ligands: PVR and Nectin2 and to inhibit human NK-cell cytotoxicity. Whether mouse TIGI...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3863769/ https://ncbi.nlm.nih.gov/pubmed/23677581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243072 |
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