Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression

Fusobacterium nucleatum is an oral anaerobe recently found to be prevalent in human colorectal cancer (CRC) where it is associated with poor treatment outcome. In mice, hematogenous F. nucleatum can colonize CRC tissue using its lectin Fap2, which attaches to tumor-displayed Gal-GalNAc. Here, we sho...

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Publicado en:Nat Commun
Main Authors: Parhi, Lishay, Alon-Maimon, Tamar, Sol, Asaf, Nejman, Deborah, Shhadeh, Amjad, Fainsod-Levi, Tanya, Yajuk, Olga, Isaacson, Batya, Abed, Jawad, Maalouf, Naseem, Nissan, Aviram, Sandbank, Judith, Yehuda-Shnaidman, Einav, Ponath, Falk, Vogel, Jörg, Mandelboim, Ofer, Granot, Zvi, Straussman, Ravid, Bachrach, Gilad
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320135/
https://ncbi.nlm.nih.gov/pubmed/32591509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16967-2
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