Fusobacterium nucleatum supresses anti-tumor immunity by activating CEACAM1

Fusobacterium nucleatum (F. nucleatum) is an oral anaerobe found to be enriched in colorectal cancer (CRC). Presence of F. nucleatum in CRC has been correlated with resistance to chemotherapy and poor prognosis. We previously demonstrated that the Fap2 outer-surface protein of F. nucleatum binds and...

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Detalhes bibliográficos
Main Authors: Chamutal Gur, Naseem Maalouf, Amjad Shhadeh, Orit Berhani, Bernhard B. Singer, Gilad Bachrach, Ofer Mandelboim
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2019-06-01
Colecção:OncoImmunology
Assuntos:
fusobacterium nucleatum
ceacam1
inhibition of killing
Acesso em linha:http://dx.doi.org/10.1080/2162402X.2019.1581531
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