Fusobacterium nucleatum CbpF Mediates Inhibition of T Cell Function Through CEACAM1 Activation

F. nucleatum is an anaerobic bacterium that is associated with several tumor entities and promotes tumorigenesis. Recent evidence suggests that F. nucleatum binds the inhibitory receptor carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1) via the trimeric autotransporter adhesin CbpF. Howeve...

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Dettagli Bibliografici
Pubblicato in:Front Cell Infect Microbiol
Autori principali: Galaski, Johanna, Shhadeh, Amjad, Umaña, Ariana, Yoo, Christopher C., Arpinati, Ludovica, Isaacson, Batya, Berhani, Orit, Singer, Bernhard B., Slade, Daniel J., Bachrach, Gilad, Mandelboim, Ofer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Cellular and Infection Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319768/
https://ncbi.nlm.nih.gov/pubmed/34336716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.692544
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