Fusobacterium nucleatum CbpF Mediates Inhibition of T Cell Function Through CEACAM1 Activation

F. nucleatum is an anaerobic bacterium that is associated with several tumor entities and promotes tumorigenesis. Recent evidence suggests that F. nucleatum binds the inhibitory receptor carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1) via the trimeric autotransporter adhesin CbpF. Howeve...

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Detalles Bibliográficos
Publicado en:Front Cell Infect Microbiol
Main Authors: Galaski, Johanna, Shhadeh, Amjad, Umaña, Ariana, Yoo, Christopher C., Arpinati, Ludovica, Isaacson, Batya, Berhani, Orit, Singer, Bernhard B., Slade, Daniel J., Bachrach, Gilad, Mandelboim, Ofer
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Cellular and Infection Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319768/
https://ncbi.nlm.nih.gov/pubmed/34336716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.692544
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