Repurposing Pyramax®, quinacrine and tilorone as treatments for Ebola virus disease

We have recently identified three molecules (tilorone, quinacrine and pyronaridine tetraphosphate) which all demonstrated efficacy in the mouse model of infection with mouse-adapted Ebola virus (EBOV) model of disease and had similar in vitro inhibition of an Ebola pseudovirus (VSV-EBOV-GP), suggest...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Antiviral Res
Päätekijät: Lane, Thomas R., Dyall, Julie, Mercer, Luke, Goodin, Caleb, Foil, Daniel H., Zhou, Huanying, Postnikova, Elena, Liang, Janie Y., Holbrook, Michael R., Madrid, Peter B., Ekins, Sean
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier B.V. 2020
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425680/
https://ncbi.nlm.nih.gov/pubmed/32798602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2020.104908
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