Repurposing Pyramax®, quinacrine and tilorone as treatments for Ebola virus disease

We have recently identified three molecules (tilorone, quinacrine and pyronaridine tetraphosphate) which all demonstrated efficacy in the mouse model of infection with mouse-adapted Ebola virus (EBOV) model of disease and had similar in vitro inhibition of an Ebola pseudovirus (VSV-EBOV-GP), suggest...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Antiviral Res
Hauptverfasser: Lane, Thomas R., Dyall, Julie, Mercer, Luke, Goodin, Caleb, Foil, Daniel H., Zhou, Huanying, Postnikova, Elena, Liang, Janie Y., Holbrook, Michael R., Madrid, Peter B., Ekins, Sean
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier B.V. 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425680/
https://ncbi.nlm.nih.gov/pubmed/32798602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2020.104908
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