Blood DNA methylation sites predict death risk in a longitudinal study of 12,300 individuals

DNA methylation has fundamental roles in gene programming and aging that may help predict mortality. However, no large-scale study has investigated whether site-specific DNA methylation predicts all-cause mortality. We used the Illumina-HumanMethylation450-BeadChip to identify blood DNA methylation...

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Bibliographic Details
Published in:Aging (Albany NY)
Main Authors: Colicino, Elena, Marioni, Riccardo, Ward-Caviness, Cavin, Gondalia, Rahul, Guan, Weihua, Chen, Brian, Tsai, Pei-Chien, Huan, Tianxiao, Xu, Gao, Golareh, Agha, Schwartz, Joel, Vokonas, Pantel, Just, Allan, Starr, John M., McRae, Allan F., Wray, Naomi R., Visscher, Peter M., Bressler, Jan, Zhang, Wen, Tanaka, Toshiko, Moore, Ann Zenobia, Pilling, Luke C., Zhang, Guosheng, Stewart, James D., Li, Yun, Hou, Lifang, Castillo-Fernandez, Juan, Spector, Tim, Kiel, Douglas P., Murabito, Joanne M., Liu, Chunyu, Mendelson, Mike, Assimes, Tim, Absher, Devin, Tsaho, Phil S., Lu, Ake T., Ferrucci, Luigi, Wilson, Rory, Waldenberger, Melanie, Prokisch, Holger, Bandinelli, Stefania, Bell, Jordana T., Levy, Daniel, Deary, Ian J., Horvath, Steve, Pankow, Jim, Peters, Annette, Whitsel, Eric A., Baccarelli, Andrea
Format: Artigo
Language:Inglês
Published: Impact Journals 2020
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425458/
https://ncbi.nlm.nih.gov/pubmed/32697766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103408
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