Blood DNA methylation sites predict death risk in a longitudinal study of 12,300 individuals

DNA methylation has fundamental roles in gene programming and aging that may help predict mortality. However, no large-scale study has investigated whether site-specific DNA methylation predicts all-cause mortality. We used the Illumina-HumanMethylation450-BeadChip to identify blood DNA methylation...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Colicino, Elena, Marioni, Riccardo, Ward-Caviness, Cavin, Gondalia, Rahul, Guan, Weihua, Chen, Brian, Tsai, Pei-Chien, Huan, Tianxiao, Xu, Gao, Golareh, Agha, Schwartz, Joel, Vokonas, Pantel, Just, Allan, Starr, John M., McRae, Allan F., Wray, Naomi R., Visscher, Peter M., Bressler, Jan, Zhang, Wen, Tanaka, Toshiko, Moore, Ann Zenobia, Pilling, Luke C., Zhang, Guosheng, Stewart, James D., Li, Yun, Hou, Lifang, Castillo-Fernandez, Juan, Spector, Tim, Kiel, Douglas P., Murabito, Joanne M., Liu, Chunyu, Mendelson, Mike, Assimes, Tim, Absher, Devin, Tsaho, Phil S., Lu, Ake T., Ferrucci, Luigi, Wilson, Rory, Waldenberger, Melanie, Prokisch, Holger, Bandinelli, Stefania, Bell, Jordana T., Levy, Daniel, Deary, Ian J., Horvath, Steve, Pankow, Jim, Peters, Annette, Whitsel, Eric A., Baccarelli, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425458/
https://ncbi.nlm.nih.gov/pubmed/32697766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103408
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