Blood DNA methylation sites predict death risk in a longitudinal study of 12,300 individuals

DNA methylation has fundamental roles in gene programming and aging that may help predict mortality. However, no large-scale study has investigated whether site-specific DNA methylation predicts all-cause mortality. We used the Illumina-HumanMethylation450-BeadChip to identify blood DNA methylation...

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書誌詳細
出版年:Aging (Albany NY)
主要な著者: Colicino, Elena, Marioni, Riccardo, Ward-Caviness, Cavin, Gondalia, Rahul, Guan, Weihua, Chen, Brian, Tsai, Pei-Chien, Huan, Tianxiao, Xu, Gao, Golareh, Agha, Schwartz, Joel, Vokonas, Pantel, Just, Allan, Starr, John M., McRae, Allan F., Wray, Naomi R., Visscher, Peter M., Bressler, Jan, Zhang, Wen, Tanaka, Toshiko, Moore, Ann Zenobia, Pilling, Luke C., Zhang, Guosheng, Stewart, James D., Li, Yun, Hou, Lifang, Castillo-Fernandez, Juan, Spector, Tim, Kiel, Douglas P., Murabito, Joanne M., Liu, Chunyu, Mendelson, Mike, Assimes, Tim, Absher, Devin, Tsaho, Phil S., Lu, Ake T., Ferrucci, Luigi, Wilson, Rory, Waldenberger, Melanie, Prokisch, Holger, Bandinelli, Stefania, Bell, Jordana T., Levy, Daniel, Deary, Ian J., Horvath, Steve, Pankow, Jim, Peters, Annette, Whitsel, Eric A., Baccarelli, Andrea
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals 2020
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425458/
https://ncbi.nlm.nih.gov/pubmed/32697766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103408
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