Blood DNA methylation sites predict death risk in a longitudinal study of 12,300 individuals

DNA methylation has fundamental roles in gene programming and aging that may help predict mortality. However, no large-scale study has investigated whether site-specific DNA methylation predicts all-cause mortality. We used the Illumina-HumanMethylation450-BeadChip to identify blood DNA methylation...

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Dettagli Bibliografici
Pubblicato in:Aging (Albany NY)
Autori principali: Colicino, Elena, Marioni, Riccardo, Ward-Caviness, Cavin, Gondalia, Rahul, Guan, Weihua, Chen, Brian, Tsai, Pei-Chien, Huan, Tianxiao, Xu, Gao, Golareh, Agha, Schwartz, Joel, Vokonas, Pantel, Just, Allan, Starr, John M., McRae, Allan F., Wray, Naomi R., Visscher, Peter M., Bressler, Jan, Zhang, Wen, Tanaka, Toshiko, Moore, Ann Zenobia, Pilling, Luke C., Zhang, Guosheng, Stewart, James D., Li, Yun, Hou, Lifang, Castillo-Fernandez, Juan, Spector, Tim, Kiel, Douglas P., Murabito, Joanne M., Liu, Chunyu, Mendelson, Mike, Assimes, Tim, Absher, Devin, Tsaho, Phil S., Lu, Ake T., Ferrucci, Luigi, Wilson, Rory, Waldenberger, Melanie, Prokisch, Holger, Bandinelli, Stefania, Bell, Jordana T., Levy, Daniel, Deary, Ian J., Horvath, Steve, Pankow, Jim, Peters, Annette, Whitsel, Eric A., Baccarelli, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals 2020
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425458/
https://ncbi.nlm.nih.gov/pubmed/32697766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103408
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