Development of a highly sensitive method for detection of FLT3D835Y

BACKGROUND: Acute myeloid leukemia (AML) is a malignant hematological neoplasm of myeloid progenitor cells. Mutations of FLT3 in its tyrosine kinase domain (FLT3-TKD) are found in ~ 8% of patients with AML, with D835Y as the most common substitution. This mutation activates survival signals that dri...

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Dades bibliogràfiques
Publicat a:Biomark Res
Autors principals: Guo, Yao, Sun, Honghua, Zhang, Dengyang, Zhao, Yuming, Shi, Mingxia, Yang, Ming, Xing, Shu, Fu, Xueqi, Bin, Ting, Lu, Bo, Wu, Shunjie, Xu, Xiaojun, Xu, Xuesong, Chen, Yun, Zhao, Zhizhuang Joe
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Methodology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424998/
https://ncbi.nlm.nih.gov/pubmed/32817792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-020-00210-7
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