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SU11652 Inhibits tyrosine kinase activity of FLT3 and growth of MV-4-11 cells
BACKGROUND: FLT3-ITD and FLT3-TKD mutations are frequently found in acute myeloid leukemia (AML). This makes tyrosine kinase FLT3 a highly attractive target for therapeutic drug development. However, effective drugs have not yet emerged. This study is intended to identify and to characterize new FLT...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3524753/ https://ncbi.nlm.nih.gov/pubmed/23216927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-5-72 |
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