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Cathepsin B/ SAPC inhibition deregulates apoptosis-related proteins in neuronal cells exposed to supernatants from HIV-infected macrophages
Monocytes infected with Human immunodeficiency virus 1 (HIV-1) can cross the blood-brain barrier to the central nervous system facilitating neuronal damage. Brain monocyte-derived macrophages can induce HIV neurocognitive disorders (HAND) by releasing neurotoxic factors. One of these secreted factor...
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| Publicado no: | J Biomol Tech |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Association of Biomolecular Resource Facilities
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7424844/ |
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