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Interleukin-2 drives cortisol secretion in an age-, dose-, and body composition-dependent way

BACKGROUND: Interleukin-2 (IL-2), one of the proinflammatory cytokines, is used in the treatment of certain malignancies. In some studies, transient increases in cortisol and ACTH secretion occurred. Thus, this agent may be used as an experimental probe of adrenal cortisol secretion. OBJECTIVE: This...

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Bibliografische gegevens
Gepubliceerd in:Endocr Connect
Hoofdauteurs: Roelfsema, Ferdinand, Liu, Peter Y, Yang, Rebecca, Takahashi, Paul, Veldhuis, Johannes D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Bioscientifica Ltd 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424344/
https://ncbi.nlm.nih.gov/pubmed/32520721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-20-0211
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