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Interleukin-2 drives cortisol secretion in an age-, dose-, and body composition-dependent way

BACKGROUND: Interleukin-2 (IL-2), one of the proinflammatory cytokines, is used in the treatment of certain malignancies. In some studies, transient increases in cortisol and ACTH secretion occurred. Thus, this agent may be used as an experimental probe of adrenal cortisol secretion. OBJECTIVE: This...

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Publicat a:Endocr Connect
Autors principals: Roelfsema, Ferdinand, Liu, Peter Y, Yang, Rebecca, Takahashi, Paul, Veldhuis, Johannes D
Format: Artigo
Idioma:Inglês
Publicat: Bioscientifica Ltd 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424344/
https://ncbi.nlm.nih.gov/pubmed/32520721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-20-0211
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