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SUN-309 Interleukin-2 Administration in Healthy Men Activates Cortisol Secretion in an Age-, Dose-, and Body Composition-Dependent Way

Context. Interleukin-2 (IL2), a proinflammatory cytokine, is used for treatment of malignancies. Increased cortisol and ACTH were noted, but not investigated in detail. This is the first study in healthy men which uses moderate high IL2 doses as used in cancer treatment. Objective. The goal of this...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Roelfsema, Ferdinand, Liu, Peter Y, Yang, Rebecca, Takahashi, Paul, Veldhuis, Johannes D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208466/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.089
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